Lidocaine inhibits the lung cancer progression through decreasing the HIST1H2BL levels via SIRT5 mediated succinylation
Abstract Lung cancer is a malignant tumor originating from the bronchial mucosa or gland of the lung.Recently, lidocaine, a widely used amide local anesthetic, was demonstrated to inhibit many cancer progression.This research was performed to explore the specific mechanism of lidocaine in the lung cancer progression.The human normal lung epithelial